The Science Inside Every Bite
When it comes to your health journey, what you eat sets the foundation for how your body functions.
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Backed by Science, Powered by People.
Trilivy is developed by experts, refined over decades and delivered through real human connection.
It’s not only how much weight you lose — it’s the quality of the weight lost that matters most.
Health isn’t one dimensional.
That’s why we take a three-part approach:
Nutrition Science
Behavioral Health Science
Metabolic Health Science
Our Clinical Trial.
Our Reset Phase is grounded in research, led by credentialed experts working alongside a scientific advisory board and validated by a randomized controlled trial — the gold standard in research.
Reverses metabolic dysfunction
Improves body composition
Reduces visceral fat by 14%
Retains 98% lean mass
Promotes 10x more weight loss than going it alone**
Promotes 17x more fat loss than going it alone**
Protects healthy muscle
Improves metabolic health
In as little as 16 weeks.
See All Studies*In a clinical study, individuals on the Reset Plan experienced a reduction of 14% visceral fat and 98% of lean mass was retained at 16 weeks. Arterburn LM, Coleman CD, Kiel J, et al. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. Feb 2019;5(1):3-14. doi:10.1002/osp4.312.
What Sets Our Science Apart.
40+
years of scientific & clinical heritage
140+
peer-reviewed presentations & publications
30+
scientific research studies & analyses
Developed by physicians, scientists & dietitians
Evidence-based programs, plans & products
Scientific Advisory Board comprised of health & wellness experts
Collaborations with key academic institutions & researchers
Our Legacy.
1980s
Clinical Roots Take Hold
Our founding physicians pioneer proprietary structured nutrition to address obesity in clinical settings.
Today
Nearly Half a Century Later
More than 40 years of scientific rigor and clinical heritage guide our system, crafted by experts, refined through research — including our clinical trial, the gold standard — and proven by decades of real-world outcomes.
The Science Behind the Outcomes.
Metabolic Synchronization™ is Trilivy’s breakthrough science that underpins all we do.
Combining science-backed plans and products, personalized coaching, and healthy habit creation to reverse metabolic dysfunction and advance your metabolic health through three of the most critical drivers:
14%
Visceral Fat Reduction*
98%
lean mass Retention*
High-quality Protein
Products & plans
It works by bringing your body's energy utilization, fat burn, and muscle preservation into harmony.
The key is to shift body composition toward a body that looks better, feels better and functions at its best. Because it's not only how much weight you lose — it’s the quality of the weight lost that matters most.
The result of decades of experience and 30+ research studies, Metabolic Synchronization delivers transformative, clinically significant outcomes in as little as 16 weeks.
It’s not only how much weight you lose — it’s the quality of the weight lost that matters most.
Our Experts.
Trilivy’s Scientific & Clinical Affairs and Research & Development teams bring together experts in nutrition science, exercise science, public health, behavior change and food science — merging scientific discovery with real-world application.
Satya Jonnalagadda
PhD · MBA · RDN
Vice President of Scientific & Clinical Affairs
Doug Zimmermann
Vice President of Research and Development
Jessica Kiel
MS · RDN · LDN · CPT · CCRP · FAND
Principal Scientist
Patrice A. Hubert
PhD · RDN
Principal Healthcare Scientist
Shannon Davis
Senior Director of Research & Development
Madelyn Shepherd
MPH · CHES®
Senior Health and Nutrition Educator
Alexandra Miller
MS · RDN
Senior Corporate Dietitian
Christopher Coleman
MS · RDN · LDN · CPT · CCRP
Senior Principal Scientist
Jennifer Christman
MHA · RDN · LDN · CPT
Senior Manager of Nutrition and Wellness
Dr. Wayne Scott Andersen.
MMHI distinguished fellow and Independent Trilivy Coach | New York Times Bestselling Author
Dr. Wayne Scott Andersen (Dr. A) left his career as a critical care physician with a singular mission: to teach people how to prevent disease through an evidence-based behavior change system. As the creator of Dr. A’s Habits of Health Transformational System, his pioneering work in habit formation remains central to our three-part metabolic health system.
Our Scientific Advisory Board.
Dr. Steven Heymsfield
Professor & Director
Body Composition–Metabolism Laboratory, Pennington Biomedical Research Center, LSU
Dr. Jessica Unick
Professor of Psychiatry & Human Behavior
Brown Alpert Medical School · Miriam Hospital’s Weight Control & Diabetes Research Center
Dr. Nik Dhurandhar
Professor & Chairperson, Department of Nutritional Sciences
Texas Tech University
Editor-in-Chief
International Journal of Obesity
Dr. Shawn Arent
Professor & Chair, Department of Exercise Science
University of South Carolina
Director, USC Sport Science Lab
Dr. J. Graham Thomas
Professor of Public Health and Nutrition at the University of Tennessee
Dr. Holly Lofton
Director of Medical Weight Management Program at NYU School of Medicine. Clinical Associate Professor at NYU Grossman School of Medicine.
Our Institute for Metabolic Health
The Medifast Metabolic Health Institute™ advances the field through rigorous research and credible, evidence-based education that drives informed action and lasting health transformation.
Our Purpose
Elevating the importance of metabolic health as a cornerstone of well-being
Translating science into actionable knowledge
Empowering individuals to develop healthy habits that support optimal metabolic health
Defining the future of optimal metabolic health
Steeped in scientific excellence, the institute is led by a multidisciplinary team of internal scientists, health professionals, and nutrition and wellness experts. Our work is guided by Dr. Wayne Scott Andersen and the Medifast Scientific Advisory Board — a group of internationally recognized experts in medical care, education, nutrition, exercise and biobehavioral science, body composition, metabolism, and digital health.
Learn MoreMurphy SL, Kochanek KD, Xu JQ, Arias E. Mortality in the United States, 2023. NCHS Data Brief, no 521. Hyattsville, MD: National Center for Health Statistics. 2024. doi: 10.15620/cdc/170564.
Important Clinical Disclosures:
Average weight loss on the Reset Plan is 12 pounds. Clients are in weight loss, on average, for 12 weeks. Arterburn LM, Coleman CD, Kiel J, et al. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. Feb 2019;5 (1):3-14. doi:10.1002/osp4.312
*In a clinical study, individuals on the Reset Plan experienced a reduction of 14% visceral fat and 98% of lean mass was retained at 16 weeks. Arterburn LM, Coleman CD, Kiel J, et al. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. Feb 2019;5 (1):3-14. doi:10.1002/osp4.312.
**In a clinical study, individuals on the Reset Plan with support of a Trilivy™ coach successfully lost 10x more weight and 17x more fat than those who tried to lose weight on their own. Arterburn LM, Coleman CD, Kiel J, et al. Randomized controlled trial assessing two commercial weight loss programs in adults with overweight or obesity. Obes Sci Pract. Feb 2019;5 (1):3-14. doi:10.1002/osp4.312.
